Review



molecule compound library  (TargetMol)


Bioz Verified Symbol TargetMol is a verified supplier
Bioz Manufacturer Symbol TargetMol manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 93
      Buy from Supplier

    Structured Review

    TargetMol molecule compound library
    Screening <t>of</t> <t>small-molecule</t> compounds targeting ANKRD22. A Schematic diagram of the virtual screening process for ANKRD22 small-molecule compounds. B LS-174 T cells were treated with small-molecule compounds at concentrations ranging from 0.1–10 μM for 24 h. WB analysis was performed to measure the levels of ANKRD22 in cells treated with 12 candidate small-molecule compounds. C Determination of the IC 50 values of four candidate small-molecule compounds. The horizontal axis is on a logarithmic scale (μM). D Effects of candidate small-molecule compounds on the expression of ANKRD22 in macrophages derived from THP-1 cells. E FCM analysis of the impact of Compound 3 on the expression of CD86 in macrophages derived from THP-1 cells. Macrophages derived from THP-1 cells were cotreated with 5 μM of Compound 3 and 1 ng/mL of IFN-γ for 24 h
    Molecule Compound Library, supplied by TargetMol, used in various techniques. Bioz Stars score: 93/100, based on 6 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/molecule compound library/product/TargetMol
    Average 93 stars, based on 6 article reviews
    molecule compound library - by Bioz Stars, 2026-05
    93/100 stars

    Images

    1) Product Images from "ANKRD22 participates in the proinflammatory activities of macrophages in the colon cancer tumor microenvironment"

    Article Title: ANKRD22 participates in the proinflammatory activities of macrophages in the colon cancer tumor microenvironment

    Journal: Cancer Immunology, Immunotherapy : CII

    doi: 10.1007/s00262-024-03930-z

    Screening of small-molecule compounds targeting ANKRD22. A Schematic diagram of the virtual screening process for ANKRD22 small-molecule compounds. B LS-174 T cells were treated with small-molecule compounds at concentrations ranging from 0.1–10 μM for 24 h. WB analysis was performed to measure the levels of ANKRD22 in cells treated with 12 candidate small-molecule compounds. C Determination of the IC 50 values of four candidate small-molecule compounds. The horizontal axis is on a logarithmic scale (μM). D Effects of candidate small-molecule compounds on the expression of ANKRD22 in macrophages derived from THP-1 cells. E FCM analysis of the impact of Compound 3 on the expression of CD86 in macrophages derived from THP-1 cells. Macrophages derived from THP-1 cells were cotreated with 5 μM of Compound 3 and 1 ng/mL of IFN-γ for 24 h
    Figure Legend Snippet: Screening of small-molecule compounds targeting ANKRD22. A Schematic diagram of the virtual screening process for ANKRD22 small-molecule compounds. B LS-174 T cells were treated with small-molecule compounds at concentrations ranging from 0.1–10 μM for 24 h. WB analysis was performed to measure the levels of ANKRD22 in cells treated with 12 candidate small-molecule compounds. C Determination of the IC 50 values of four candidate small-molecule compounds. The horizontal axis is on a logarithmic scale (μM). D Effects of candidate small-molecule compounds on the expression of ANKRD22 in macrophages derived from THP-1 cells. E FCM analysis of the impact of Compound 3 on the expression of CD86 in macrophages derived from THP-1 cells. Macrophages derived from THP-1 cells were cotreated with 5 μM of Compound 3 and 1 ng/mL of IFN-γ for 24 h

    Techniques Used: Expressing, Derivative Assay



    Similar Products

    molecule compound library  (TargetMol)
    93
    TargetMol molecule compound library
    Screening <t>of</t> <t>small-molecule</t> compounds targeting ANKRD22. A Schematic diagram of the virtual screening process for ANKRD22 small-molecule compounds. B LS-174 T cells were treated with small-molecule compounds at concentrations ranging from 0.1–10 μM for 24 h. WB analysis was performed to measure the levels of ANKRD22 in cells treated with 12 candidate small-molecule compounds. C Determination of the IC 50 values of four candidate small-molecule compounds. The horizontal axis is on a logarithmic scale (μM). D Effects of candidate small-molecule compounds on the expression of ANKRD22 in macrophages derived from THP-1 cells. E FCM analysis of the impact of Compound 3 on the expression of CD86 in macrophages derived from THP-1 cells. Macrophages derived from THP-1 cells were cotreated with 5 μM of Compound 3 and 1 ng/mL of IFN-γ for 24 h
    Molecule Compound Library, supplied by TargetMol, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/molecule compound library/product/TargetMol
    Average 93 stars, based on 1 article reviews
    molecule compound library - by Bioz Stars, 2026-05
    93/100 stars
    		  Buy from Supplier
    small molecule dpp4 screening model  (Cell Signaling Technology Inc)
    90
    Cell Signaling Technology Inc small molecule dpp4 screening model
    Screening <t>of</t> <t>small-molecule</t> compounds targeting ANKRD22. A Schematic diagram of the virtual screening process for ANKRD22 small-molecule compounds. B LS-174 T cells were treated with small-molecule compounds at concentrations ranging from 0.1–10 μM for 24 h. WB analysis was performed to measure the levels of ANKRD22 in cells treated with 12 candidate small-molecule compounds. C Determination of the IC 50 values of four candidate small-molecule compounds. The horizontal axis is on a logarithmic scale (μM). D Effects of candidate small-molecule compounds on the expression of ANKRD22 in macrophages derived from THP-1 cells. E FCM analysis of the impact of Compound 3 on the expression of CD86 in macrophages derived from THP-1 cells. Macrophages derived from THP-1 cells were cotreated with 5 μM of Compound 3 and 1 ng/mL of IFN-γ for 24 h
    Small Molecule Dpp4 Screening Model, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/small molecule dpp4 screening model/product/Cell Signaling Technology Inc
    Average 90 stars, based on 1 article reviews
    small molecule dpp4 screening model - by Bioz Stars, 2026-05
    90/100 stars
    		  Buy from Supplier
    high content screening of small molecules  (Broad Institute Inc)
    90
    Broad Institute Inc high content screening of small molecules
    Screening <t>of</t> <t>small-molecule</t> compounds targeting ANKRD22. A Schematic diagram of the virtual screening process for ANKRD22 small-molecule compounds. B LS-174 T cells were treated with small-molecule compounds at concentrations ranging from 0.1–10 μM for 24 h. WB analysis was performed to measure the levels of ANKRD22 in cells treated with 12 candidate small-molecule compounds. C Determination of the IC 50 values of four candidate small-molecule compounds. The horizontal axis is on a logarithmic scale (μM). D Effects of candidate small-molecule compounds on the expression of ANKRD22 in macrophages derived from THP-1 cells. E FCM analysis of the impact of Compound 3 on the expression of CD86 in macrophages derived from THP-1 cells. Macrophages derived from THP-1 cells were cotreated with 5 μM of Compound 3 and 1 ng/mL of IFN-γ for 24 h
    High Content Screening Of Small Molecules, supplied by Broad Institute Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/high content screening of small molecules/product/Broad Institute Inc
    Average 90 stars, based on 1 article reviews
    high content screening of small molecules - by Bioz Stars, 2026-05
    90/100 stars
    		  Buy from Supplier
    small molecule screening and initial compound retesting  (WuXi AppTec)
    90
    WuXi AppTec small molecule screening and initial compound retesting
    Screening <t>of</t> <t>small-molecule</t> compounds targeting ANKRD22. A Schematic diagram of the virtual screening process for ANKRD22 small-molecule compounds. B LS-174 T cells were treated with small-molecule compounds at concentrations ranging from 0.1–10 μM for 24 h. WB analysis was performed to measure the levels of ANKRD22 in cells treated with 12 candidate small-molecule compounds. C Determination of the IC 50 values of four candidate small-molecule compounds. The horizontal axis is on a logarithmic scale (μM). D Effects of candidate small-molecule compounds on the expression of ANKRD22 in macrophages derived from THP-1 cells. E FCM analysis of the impact of Compound 3 on the expression of CD86 in macrophages derived from THP-1 cells. Macrophages derived from THP-1 cells were cotreated with 5 μM of Compound 3 and 1 ng/mL of IFN-γ for 24 h
    Small Molecule Screening And Initial Compound Retesting, supplied by WuXi AppTec, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/small molecule screening and initial compound retesting/product/WuXi AppTec
    Average 90 stars, based on 1 article reviews
    small molecule screening and initial compound retesting - by Bioz Stars, 2026-05
    90/100 stars
    		  Buy from Supplier
    cell-based small-molecule screening  (Proteostasis Therapeutics)
    90
    Proteostasis Therapeutics cell-based small-molecule screening
    Screening <t>of</t> <t>small-molecule</t> compounds targeting ANKRD22. A Schematic diagram of the virtual screening process for ANKRD22 small-molecule compounds. B LS-174 T cells were treated with small-molecule compounds at concentrations ranging from 0.1–10 μM for 24 h. WB analysis was performed to measure the levels of ANKRD22 in cells treated with 12 candidate small-molecule compounds. C Determination of the IC 50 values of four candidate small-molecule compounds. The horizontal axis is on a logarithmic scale (μM). D Effects of candidate small-molecule compounds on the expression of ANKRD22 in macrophages derived from THP-1 cells. E FCM analysis of the impact of Compound 3 on the expression of CD86 in macrophages derived from THP-1 cells. Macrophages derived from THP-1 cells were cotreated with 5 μM of Compound 3 and 1 ng/mL of IFN-γ for 24 h
    Cell Based Small Molecule Screening, supplied by Proteostasis Therapeutics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/cell-based small-molecule screening/product/Proteostasis Therapeutics
    Average 90 stars, based on 1 article reviews
    cell-based small-molecule screening - by Bioz Stars, 2026-05
    90/100 stars
    		  Buy from Supplier
    cell titer-glo data from oci-ly1 cayman epigenetic small molecule screen  (Cayman Chemical)
    90
    Cayman Chemical cell titer-glo data from oci-ly1 cayman epigenetic small molecule screen
    Screening <t>of</t> <t>small-molecule</t> compounds targeting ANKRD22. A Schematic diagram of the virtual screening process for ANKRD22 small-molecule compounds. B LS-174 T cells were treated with small-molecule compounds at concentrations ranging from 0.1–10 μM for 24 h. WB analysis was performed to measure the levels of ANKRD22 in cells treated with 12 candidate small-molecule compounds. C Determination of the IC 50 values of four candidate small-molecule compounds. The horizontal axis is on a logarithmic scale (μM). D Effects of candidate small-molecule compounds on the expression of ANKRD22 in macrophages derived from THP-1 cells. E FCM analysis of the impact of Compound 3 on the expression of CD86 in macrophages derived from THP-1 cells. Macrophages derived from THP-1 cells were cotreated with 5 μM of Compound 3 and 1 ng/mL of IFN-γ for 24 h
    Cell Titer Glo Data From Oci Ly1 Cayman Epigenetic Small Molecule Screen, supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/cell titer-glo data from oci-ly1 cayman epigenetic small molecule screen/product/Cayman Chemical
    Average 90 stars, based on 1 article reviews
    cell titer-glo data from oci-ly1 cayman epigenetic small molecule screen - by Bioz Stars, 2026-05
    90/100 stars
    		  Buy from Supplier
    small molecule screening compound series  (MolPort Inc)
    90
    MolPort Inc small molecule screening compound series
    Screening <t>of</t> <t>small-molecule</t> compounds targeting ANKRD22. A Schematic diagram of the virtual screening process for ANKRD22 small-molecule compounds. B LS-174 T cells were treated with small-molecule compounds at concentrations ranging from 0.1–10 μM for 24 h. WB analysis was performed to measure the levels of ANKRD22 in cells treated with 12 candidate small-molecule compounds. C Determination of the IC 50 values of four candidate small-molecule compounds. The horizontal axis is on a logarithmic scale (μM). D Effects of candidate small-molecule compounds on the expression of ANKRD22 in macrophages derived from THP-1 cells. E FCM analysis of the impact of Compound 3 on the expression of CD86 in macrophages derived from THP-1 cells. Macrophages derived from THP-1 cells were cotreated with 5 μM of Compound 3 and 1 ng/mL of IFN-γ for 24 h
    Small Molecule Screening Compound Series, supplied by MolPort Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/small molecule screening compound series/product/MolPort Inc
    Average 90 stars, based on 1 article reviews
    small molecule screening compound series - by Bioz Stars, 2026-05
    90/100 stars
    		  Buy from Supplier
    small molecule screen  (Praxis Precision Medicines Inc)
    90
    Praxis Precision Medicines Inc small molecule screen
    Screening <t>of</t> <t>small-molecule</t> compounds targeting ANKRD22. A Schematic diagram of the virtual screening process for ANKRD22 small-molecule compounds. B LS-174 T cells were treated with small-molecule compounds at concentrations ranging from 0.1–10 μM for 24 h. WB analysis was performed to measure the levels of ANKRD22 in cells treated with 12 candidate small-molecule compounds. C Determination of the IC 50 values of four candidate small-molecule compounds. The horizontal axis is on a logarithmic scale (μM). D Effects of candidate small-molecule compounds on the expression of ANKRD22 in macrophages derived from THP-1 cells. E FCM analysis of the impact of Compound 3 on the expression of CD86 in macrophages derived from THP-1 cells. Macrophages derived from THP-1 cells were cotreated with 5 μM of Compound 3 and 1 ng/mL of IFN-γ for 24 h
    Small Molecule Screen, supplied by Praxis Precision Medicines Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/small molecule screen/product/Praxis Precision Medicines Inc
    Average 90 stars, based on 1 article reviews
    small molecule screen - by Bioz Stars, 2026-05
    90/100 stars
    		  Buy from Supplier
    small molecules from the epigenetics screening library cayman 11076  (Cayman Chemical)
    90
    Cayman Chemical small molecules from the epigenetics screening library cayman 11076
    Screening <t>of</t> <t>small-molecule</t> compounds targeting ANKRD22. A Schematic diagram of the virtual screening process for ANKRD22 small-molecule compounds. B LS-174 T cells were treated with small-molecule compounds at concentrations ranging from 0.1–10 μM for 24 h. WB analysis was performed to measure the levels of ANKRD22 in cells treated with 12 candidate small-molecule compounds. C Determination of the IC 50 values of four candidate small-molecule compounds. The horizontal axis is on a logarithmic scale (μM). D Effects of candidate small-molecule compounds on the expression of ANKRD22 in macrophages derived from THP-1 cells. E FCM analysis of the impact of Compound 3 on the expression of CD86 in macrophages derived from THP-1 cells. Macrophages derived from THP-1 cells were cotreated with 5 μM of Compound 3 and 1 ng/mL of IFN-γ for 24 h
    Small Molecules From The Epigenetics Screening Library Cayman 11076, supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/small molecules from the epigenetics screening library cayman 11076/product/Cayman Chemical
    Average 90 stars, based on 1 article reviews
    small molecules from the epigenetics screening library cayman 11076 - by Bioz Stars, 2026-05
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    Screening of small-molecule compounds targeting ANKRD22. A Schematic diagram of the virtual screening process for ANKRD22 small-molecule compounds. B LS-174 T cells were treated with small-molecule compounds at concentrations ranging from 0.1–10 μM for 24 h. WB analysis was performed to measure the levels of ANKRD22 in cells treated with 12 candidate small-molecule compounds. C Determination of the IC 50 values of four candidate small-molecule compounds. The horizontal axis is on a logarithmic scale (μM). D Effects of candidate small-molecule compounds on the expression of ANKRD22 in macrophages derived from THP-1 cells. E FCM analysis of the impact of Compound 3 on the expression of CD86 in macrophages derived from THP-1 cells. Macrophages derived from THP-1 cells were cotreated with 5 μM of Compound 3 and 1 ng/mL of IFN-γ for 24 h

    Journal: Cancer Immunology, Immunotherapy : CII

    Article Title: ANKRD22 participates in the proinflammatory activities of macrophages in the colon cancer tumor microenvironment

    doi: 10.1007/s00262-024-03930-z

    Figure Lengend Snippet: Screening of small-molecule compounds targeting ANKRD22. A Schematic diagram of the virtual screening process for ANKRD22 small-molecule compounds. B LS-174 T cells were treated with small-molecule compounds at concentrations ranging from 0.1–10 μM for 24 h. WB analysis was performed to measure the levels of ANKRD22 in cells treated with 12 candidate small-molecule compounds. C Determination of the IC 50 values of four candidate small-molecule compounds. The horizontal axis is on a logarithmic scale (μM). D Effects of candidate small-molecule compounds on the expression of ANKRD22 in macrophages derived from THP-1 cells. E FCM analysis of the impact of Compound 3 on the expression of CD86 in macrophages derived from THP-1 cells. Macrophages derived from THP-1 cells were cotreated with 5 μM of Compound 3 and 1 ng/mL of IFN-γ for 24 h

    Article Snippet: The small-molecule compound library used was the Topscience Database, which comprises 7,272,880 compounds.

    Techniques: Expressing, Derivative Assay